For three decades we have heard about the hope of tissue engineering. Hyperbole has become routine, but amidst unreasonable expectations are serious scientists, like Paulo Macchiarini, who believe that by combining cells and degradable materials ex vivo they can develop organs to replace or repair diseased tissues. After many years of trying to build engineered tissues on a backbone of synthetic degradable polymers, a growing body of evidence suggests that decellularised whole organs and tissues are clinically effective degradable scaffolds.
View full article in the Lancet here
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